Iron deficiency in cardiac surgical patients

Keywords:

Iron deficiency, anaemia, intravenous iron supplementation, hepcidin


Published online: Feb 21 2023

https://doi.org/10.56126/73.4.28

L. Hof1, O. Old1, A. U. Steinbicker1, P. Meybohm2, S. Choorapoikayil1, K. Zacharowski1

1 Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Frankfurt, Germany
2 Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany

Abstract

Iron is an essential element and involved in a variety of metabolic processes including oxygen transport, cellular energy production, energy metabolism of heart muscles, brain function, cell growth and cell differentiation. Preoperative anaemia is an independent risk factor for poor outcome. Recently, iron deficiency was considered only in the context of anaemia. However, negative consequences of iron deficiency in the absence of anaemia have been described for patients undergoing cardiac surgery. To date, the benefit of intravenous iron supplementation in these patients has been controversially debated. In this review, we discuss the latest progress in studies of intravenous iron supplementation in iron deficient cardiac surgical patients.

ActaAnaestBelg-73-4-cover

About this issue

Volume 73, issue 4.

Sep 2022.

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